At our facility, we utilize the Hyperoxic-Hypoxic Paradox (HHP) protocol that in numerous studies has been shown to activate the body’s natural regenerative and restorative processes better than anything currently known to man.  

 

The HHP is a result of 15+ years of research performed by Dr. Shai Efrati and the Sagol Center for Hyperbaric Medicine and Research in Israel.

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In a standard 90-minute HBOT session, individuals alternate between breathing pure oxygen through a mask for 20 minutes and then remove the mask for a 5 - minute break, breathing the chamber’s normal/ambient air supply. This cycle is repeated throughout the session.

 

The shift from breathing high oxygen through the mask (hyperoxia) for 20 minutes and then removing the mask for 5 minutes and breathing normal air oxygen levels, creates a signal at the cellular level similar to that of a low-oxygen environment (hypoxia), but without the risks of true hypoxia.

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Extensive research has shown that HHP influences pathways related to tissue repair, vascular recovery, inflammation regulation, and cellular support.

 

Documented effects include an 800% increase in stem cell production, a 25–30% increase in telomere length, a 30% reduction in senescent (“zombie”) cells, and measurable improvements in mitochondrial function and density.

 

Additional findings point to modulation of cell signaling molecules and growth factors such as HIF-1, Sirtuins, MMP, VEGF, and BDNF.  which are associated with circulation and regeneration.

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In summary: The HHP uses controlled oxygen exposure to stimulate regenerative and adaptive responses that support cellular communication, vascular health, and overall wellness.